Bioassay-directed isolation of quaternary benzylisoquinolines from Berberis integerrima with bactericidal activity against Brucella abortus
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چکیده
منابع مشابه
Bactericidal Effect of Silver Nanoparticles on Intramacrophage Brucella abortus 544
BACKGROUND Brucellosis is an infectious disease that is caused by Brucella spp. As Brucella spp. are intramacrophage pathogens, the treatment of this infection is very difficult. On the other hand, due to the side effects of the brucellosis treatment regime, it is necessary to find new antimicrobial agents against it. OBJECTIVES The aim of this study was to investigate the antimicrobial effec...
متن کاملISOLATION AND PURIFICATION OF MAJOR OUTER MEMBRANE PROTEINS FROM BRUCELLA ABORTUS S-99
Isolation and purification of major outer membrane proteins (OMP) from the cell wall envelope of Brucella abortus S-99 were achieved by sonication, solubilization and membrane fractionation in the presence of non-ionic detergent (Tx-100) and lysozyme treatments, followed by ultracentrifugation. The crude OMP was treated with trypsin to free the preparation from any other protein contaminan...
متن کاملMultivalent Fusion DNA Vaccine against Brucella abortus
As an alternative brucellosis prevention method, we evaluated the immunogenicity induced by new multivalent DNA vaccines in BALB/c mice. We constructed the vaccines by fusion of BAB1_0273 and/or BAB1_0278 open reading frames (ORFs) from genomic island 3 (GI-3) and the Brucella abortus 2308 sodC gene with a link based on prolines and alanines (pV273-sod, pV278-sod, and pV273-278-sod, resp.). Res...
متن کاملBioassay-directed isolation of active compounds with antiyeast activity from a Cassia fistula seed extract.
BACKGROUND AND OBJECTIVE Cassia fistula L belongs to the family Leguminosae, and it is one of the most popular herbal products in tropical countries. C. fistula seeds have been used as a herbal medicine and have pharmacological activity which includes anti-bacterial, anti-fungal, and antioxidant properties. The goal of this study was to identify compounds from C. fistula seeds which are respons...
متن کاملbactericidal effect of silver nanoparticles on intramacrophage brucella abortus 544
conclusions: the results showed that silver nanoparticles have an antimicrobial effect against intramacrophage b. abortus 544. results: the well diffusion agar study showed that silver nanoparticles have an antimicrobial effect on b. abortus 544. the mic and mbc of silver nanoparticles against b. abortus 544 were; 6 ppm and 8 ppm, respectively. the silver nanoparticles showed antibacterial effe...
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ژورنال
عنوان ژورنال: Research in Pharmaceutical Sciences
سال: 2018
ISSN: 1735-5362
DOI: 10.4103/1735-5362.223797